Lab grown kidneys test drugs without animals and more!
October 19, 2015
2015 may be considered The Year of the Lab-Grown Organ. Multiple investigators have bio-engineered sophisticated and advanced organoid models from human cells to replicate the function and anatomy of the brain, heart, and liver, among others. But the kidneys have presented special challenges.
Read moreNew advance in cancer research without animals
October 9, 2015
Cancer treatments developed using animals have consistently had a high failure rate. Less than 8% of treatments that are effective in animal models show similar success in human clinical cancer trials.
Read moreUnilever joins EPA to advance animal-free tests
September 25, 2015
In 2008 three major U.S. regulatory agencies announced the ground-breaking ToxCast initiative to reduce reliance on animals for chemical testing. Since then, the impetus to shift to non-animal test methods has continued to grow.
Read moreBrain-in-a-dish provides new model of human disease
September 10, 2015
In recent months CAARE has shared news of advances in three-dimensional human cell cultures that are increasingly able to simulate the structure and function of real organs.
Read moreNew drug partnership expands Organs-on-Chips to replace animals
August 7, 2015
The promise of organ chips to revolutionize drug development while moving away from animals continues to expand.
Read moreFirst ever model of developing human heart created
July 23, 2015
Scientists have successfully created a model of early human heart development using stem cells derived from human skin cells.
Read more"Organoids" from patient tumors may boost precision medicine
June 11, 2015
As scientists learn more about the complexity of cancer, the need for personalized treatments based on the patient’s individual cancer has become increasingly pressing.
Read moreHistoric EU hearing considers end to animal research
May 21, 2015
In an unprecedented event, the European Parliament held a hearing last week to consider an initiative calling for an end to research on animals in the EU.
Read moreMerck to incorporate simulated liver for drug testing
May 7, 2015
Merck & Co., one of the world’s largest pharmaceutical companies, is teaming up with Organovo, a U.S. biotech firm specializing in manufacturing 3D printed tissues from human cells. The result, according to Organovo’s website, is “structurally and functionally accurate bioprinted human tissue models.”
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