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A prevailing myth is that even if animal experiments are problematic at the cellular or genetic level, we can learn something from them using the basic biomechanics of physiology. But this also has proven false. A recent study on anatomical predictions of muscle measurements based on experiments in mice showed that these are incorrect and can adversely impact surgical procedures on humans.

In a huge acknowledgement that we need to move away from animal research, Swiss company Roche, the fifth-largest pharmaceutical company in the world, has just launched an Institute for Human Biology to focus on human model systems that more precisely simulate human disease than animal experiments.

CAARE is thrilled to announce that the FDA Modernization Act 2.0 has been passed today, December 23, 2022, by the U.S. Congress!

We’re having a National call-in day on Tuesday, November 1st to urge Congress to support the FDA Modernization Act, and we need your help!

Yesterday, September 29, 2022, the Senate voted unanimously to pass the bipartisan FDA Modernization Act that would lift the absolute requirement for animal testing in new drug development.

Two major breakthroughs last week paved the way for an end to the use of animals in drug tests.

This is big! Last week the House Health Subcommittee took a huge step towards passing the FDA Modernization Act, which would end FDA’s animal testing requirement, by voting 30 – 0 on May 11 to pass a legislative package that includes the Act.

There are over 200 connective tissue disorders that currently lack cures or effective treatments, many of which are seriously disabling or even fatal.

The number of scientists who affirm that animal experiments cannot deliver accurate results for human medicine is never-ending.

Earlier this month, Dr. Alirez Mashaghi, an award-winning doctor and scientist at Harvard and the Leiden Academic Centre for Drug Research left no doubt when he said: “… the high failure rates of drugs in clinical trials suggest that the differences between animals and humans are too big. Laboratory animals are therefore neither reliable models of humans disease nor good predictors of the effectiveness and toxicity of drugs.”

Please note: Due to rules imposed by the U.S. Congress, only residents of the U.S. may sign this letter.

The past twenty years have seen astounding progress in developing innovative and superior methods that can replace the use of animals in research and testing. Sophisticated cell cultures such as 3D organoids, organs on chips, along with advances in medical imaging, computer modeling and mapping the human genome have transformed science and medicine.