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NIH reveals plan to phase out animal experiments!

In a groundbreaking announcement Tuesday, April 29, 2025, the National Institutes of Health (NIH) revealed a new initiative to reduce animal experiments while expanding human-based science. The initiative comes less than three weeks after an announcement from the U.S. Food and Drug Administration (FDA) that it is implementing a phase-out plan for animal testing in drug development.

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FDA reveals phase out of animal tests!

Last week the U.S. Food and Drug Administration (FDA) issued a groundbreaking announcement that it will start to phase out some animal testing requirements with the goal of eventually moving towards using animal-free models for all new drug approval — their most significant statement on this topic to date.

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Humans are not just big mice

A prevailing myth is that even if animal experiments are problematic at the cellular or genetic level, we can learn something from them using the basic biomechanics of physiology. But this also has proven false. A recent study on anatomical predictions of muscle measurements based on experiments in mice showed that these are incorrect and can adversely impact surgical procedures on humans.

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Pharma giant opens Institute for Human Biology

In a huge acknowledgement that we need to move away from animal research, Swiss company Roche, the fifth-largest pharmaceutical company in the world, has just launched an Institute for Human Biology to focus on human model systems that more precisely simulate human disease than animal experiments.

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The FDA Modernization Act has passed!

CAARE is thrilled to announce that the FDA Modernization Act 2.0 has been passed today, December 23, 2022, by the U.S. Congress!

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Call Congress on Tuesday November 1

We’re having a National call-in day on Tuesday, November 1st to urge Congress to support the FDA Modernization Act, and we need your help!

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Victory! Senate passes FDA Modernization Act

Yesterday, September 29, 2022, the Senate voted unanimously to pass the bipartisan FDA Modernization Act that would lift the absolute requirement for animal testing in new drug development.

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Two steps forward for ending drug tests on animals

Two major breakthroughs last week paved the way for an end to the use of animals in drug tests.

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Great news! FDA bill on path for success

This is big! Last week the House Health Subcommittee took a huge step towards passing the FDA Modernization Act, which would end FDA’s animal testing requirement, by voting 30 – 0 on May 11 to pass a legislative package that includes the Act.

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A new 3D model to test treatments for fibrosis

There are over 200 connective tissue disorders that currently lack cures or effective treatments, many of which are seriously disabling or even fatal.

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