Lab grown kidneys test drugs without animals and more!

October 19, 2015

2015 may be considered The Year of the Lab-Grown Organ. Multiple investigators have bio-engineered sophisticated and advanced organoid models from human cells to replicate the function and anatomy of the brain, heart, and liver, among others. But the kidneys have presented special challenges. 

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New advance in cancer research without animals

October 9, 2015

Cancer treatments developed using animals have consistently had a high failure rate. Less than 8% of treatments that are effective in animal models show similar success in human clinical cancer trials.

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Unilever joins EPA to advance animal-free tests

September 25, 2015

In 2008 three major U.S. regulatory agencies announced the ground-breaking ToxCast initiative to reduce reliance on animals for chemical testing. Since then, the impetus to shift to non-animal test methods has continued to grow.

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Brain-in-a-dish provides new model of human disease

September 10, 2015

In recent months CAARE has shared news of advances in three-dimensional human cell cultures that are increasingly able to simulate the structure and function of real organs.

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New drug partnership expands Organs-on-Chips to replace animals

August 7, 2015

The promise of organ chips to revolutionize drug development while moving away from animals continues to expand.

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First ever model of developing human heart created

July 23, 2015

Scientists have successfully created a model of early human heart development using stem cells derived from human skin cells. 

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Virtual heart shows real compassion for animals

July 9, 2015

Dassault Systèmes announces the first virtual human heart.

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"Organoids" from patient tumors may boost precision medicine

June 11, 2015

As scientists learn more about the complexity of cancer, the need for personalized treatments based on the patient’s individual cancer has become increasingly pressing. 

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Historic EU hearing considers end to animal research

May 21, 2015

In an unprecedented event, the European Parliament held a hearing last week to consider an initiative calling for an end to research on animals in the EU. 

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Merck to incorporate simulated liver for drug testing

May 7, 2015

Merck & Co., one of the world’s largest pharmaceutical companies, is teaming up with Organovo, a U.S. biotech firm specializing in manufacturing 3D printed tissues from human cells. The result, according to Organovo’s website, is “structurally and functionally accurate bioprinted human tissue models.”

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