The case of the vanishing mice

January 9, 2016

Some 70 percent of medical studies do not adequately report the number of animals used in experiments.

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Putting a face on precision medicine

December 20, 2015

Dramatic cures are rare, but when then occur, they often provide insight into what the future of medicine holds possible.

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First animal-free platform screens drugs for kidney injury

November 16, 2015

A new breakthrough in toxicity detection has led to the first animal-free screening platform that accurately predicts the danger of drugs and other compounds on the human kidney.

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Printing human organs from cellular ink

October 30, 2015

Another new technology is poised to supersede using animals in the laboratory.

The impressive field of 3D bioprinting has resulted in the creation of functional human tissues, like nerve, heart and bone, which can be used for research and numerous clinical applications.

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Lab grown kidneys test drugs without animals and more!

October 19, 2015

2015 may be considered The Year of the Lab-Grown Organ. Multiple investigators have bio-engineered sophisticated and advanced organoid models from human cells to replicate the function and anatomy of the brain, heart, and liver, among others. But the kidneys have presented special challenges. 

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New advance in cancer research without animals

October 9, 2015

Cancer treatments developed using animals have consistently had a high failure rate. Less than 8% of treatments that are effective in animal models show similar success in human clinical cancer trials.

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Unilever joins EPA to advance animal-free tests

September 25, 2015

In 2008 three major U.S. regulatory agencies announced the ground-breaking ToxCast initiative to reduce reliance on animals for chemical testing. Since then, the impetus to shift to non-animal test methods has continued to grow.

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Brain-in-a-dish provides new model of human disease

September 10, 2015

In recent months CAARE has shared news of advances in three-dimensional human cell cultures that are increasingly able to simulate the structure and function of real organs.

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New drug partnership expands Organs-on-Chips to replace animals

August 7, 2015

The promise of organ chips to revolutionize drug development while moving away from animals continues to expand.

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First ever model of developing human heart created

July 23, 2015

Scientists have successfully created a model of early human heart development using stem cells derived from human skin cells. 

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